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Article

CD11b+Gr-1+ myeloid-derived suppressor cells reduce atherosclerotic lesion development in LDLr deficient mice.

Cardiovascular research - 1 Aug 2016

Foks Amanda C, Van Puijvelde Gijs H M, Wolbert Jolien, Kröner Mara J, Frodermann Vanessa, Van Der Heijden Thomas, Van Santbrink Peter J, Boon Louis, Bot Ilze, Kuiper Johan

Abstract excerpt

AIMS: Myeloid-derived suppressor cells (MDSCs) form a heterogeneous population of cells composed of early myeloid progenitor cells and immature myeloid cells, which strongly suppress pro-inflammatory immune cells in inflammatory diseases. Currently, it is unknown whether MDSCs contribute to atherosclerosis, a chronic inflammatory disease in which accumulation of lipoproteins in the arterial wall activates the...

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PMID: 27234908
DOI: 10.1093/cvr/cvw114

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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