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Integrative DNA methylome analysis of pan-cancer biomarkers in cancer discordant monozygotic twin-pairs

20 Jan 2016

Abstract excerpt

BACKGROUND: A key focus in cancer research is the discovery of biomarkers that accurately diagnose early lesions in non-invasive tissues. Several studies have identified malignancy-associated DNA methylation changes in blood, yet no general cancer biomarker has been identified to date. Here, we explore the potential of blood DNA methylation as a biomarker of pan-cancer (cancer of multiple different origins) in 41...

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Share to Epigenetics and DNA Methylation
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PMID: 26798410
DOI: 10.1186/s13148-016-0172-y

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