Article

Creation and Validation of the First Infinium DNA Methylation Array for the Human Imprintome

2024-01-16

Abstract excerpt

<h4>Background</h4> Differentially methylated imprint control regions (ICRs) regulate the monoallelic expression of imprinted genes. Their epigenetic dysregulation by environmental exposures throughout life results in the formation of common chronic diseases. Unfortunately, existing Infinium methylation arrays lack the ability to profile these regions adequately. Whole genome bisulfite sequencing (WGBS) is the un...

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Literature Corpus work: 94012e45-189e-535f-9d20-450d83bd69a6
DOI: 10.1101/2024.01.15.575646

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