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Genome-scale analysis of DNA methylation in colorectal cancer using Infinium HumanMethylation450 BeadChips

5 Aug 2013

Abstract excerpt

Illumina's Infinium HumanMethylation450 BeadChip arrays were used to examine genome-wide DNA methylation profiles in 22 sample pairs from colorectal cancer (CRC) and adjacent tissues and 19 colon tissue samples from cancer-free donors. We show that the methylation profiles of tumors and healthy tissue samples can be clearly distinguished from one another and that the main source of methylation variability is...

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PMID: 23867710
DOI: 10.4161/epi.25577

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