Using epigenomic studies in monozygotic twins to improve our understanding of cancer.

doi:10.2217/epi.14.13

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Article

Using epigenomic studies in monozygotic twins to improve our understanding of cancer.

Epigenomics - 1 Jun 2014

Roos Leonie, Spector Timothy D, Bell Christopher G

Abstract excerpt

Cancer is a set of diseases that exhibit not only genetic mutations but also a profoundly distorted epigenetic landscape. Over the last two decades, great advances have been made in identifying these alterations and their importance in the initiation and progression of cancer. Epigenetic changes can be seen from the very early stages in tumorigenesis and dysregulation of the epigenome has an increasingly...

Topics

Biomarkers, Tumor
CpG Islands
DNA Methylation
Epigenomics
Genetic Predisposition to Disease
Humans
Neoplasms
Twin Studies as Topic
Twins, Monozygotic

Source

Open in PubMed

Identifiers

PMID: 25111484
DOI: 10.2217/epi.14.13

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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