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Article

Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis

16 Jan 2016

Abstract excerpt

BACKGROUND: Increased circulating plasma urate concentration is associated with an increased risk of coronary heart disease, but the extent of any causative effect of urate on risk of coronary heart disease is still unclear. In this study, we aimed to clarify any causal role of urate on coronary heart disease risk using Mendelian randomisation analysis. METHODS: We first did a fixed-effects meta-analysis of the...

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PMID: 26781229
DOI: 10.1016/s2213-8587(15)00386-1

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