Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Causal Associations of Urate With Cardiovascular Risk Factors: Two-Sample Mendelian Randomization

8 Jul 2021

Abstract excerpt

Background Mendelian Randomization (MR) studies show conflicting causal associations of genetically predicted serum urate with cardiovascular risk factors (i.e., hypertension, diabetes, lipid profile, and kidney function). This study aimed to robustly investigate a causal relationship between urate and cardiovascular risk factors considering single nucleotide polymorphisms (SNPs) as instrumental variables using...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiovascular, Neuropeptides, and Oxidative Stress Research
Share to Gout, Hyperuricemia, Uric Acid
Share to Thyroid Disorders and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34306027
DOI: 10.3389/fgene.2021.687279

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Causal Associations of Urate With Cardiovascular Risk Factors: Two-Sample Mendelian RandomizationPMID 34306027Read ↗

Urate, Blood Pressure, and Cardiovascular Disease: Evidence From Mendelian Randomization and Meta-Analysis of Clinical Trials.Semantic proximity Read ↗

Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysisSemantic proximity Read ↗

Genetically determined serum urate levels and cardiovascular and other diseases in UK Biobank cohort: A phenome-wide mendelian randomization studySemantic proximity Read ↗

A Phenome-wide Mendelian Randomisation study on genetically determined serum urate levels in UK Biobank cohortSemantic proximity Read ↗

Urate, blood pressure and cardiovascular disease: updated evidence from Mendelian randomization and meta-analysis of clinical trialsSemantic proximity Read ↗

Investigating a possible causal relationship between maternal serum urate concentrations and offspring birthweight: a Mendelian randomization study.Semantic proximity Read ↗

Sex-specific effect of serum urate levels on coronary heart disease and myocardial infarction prevention: A Mendelian randomization study.Semantic proximity Read ↗

Mendelian randomization analysis to examine for a causal effect of urate on bone mineral density.Semantic proximity Read ↗

Causal relationship between serum uric acid and cardiovascular disease: A Mendelian randomization studySemantic proximity Read ↗

Genetically predicted serum urate levels have no causal role on depression or other psychiatric disorders.Semantic proximity Read ↗

Causal Assessment of Serum Urate Levels in Cardiometabolic Diseases Through a Mendelian Randomization Study.Semantic proximity Read ↗

Genetic susceptibility to uric acid and selected cardiovascular outcomes: a systematic review and meta-analysis of Mendelian randomization studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.