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Article

Sex-specific effect of serum urate levels on coronary heart disease and myocardial infarction prevention: A Mendelian randomization study.

Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 May 2022

Yang Fangkun, Lu Yunlong, Chen Songzan, Wang Kai, Hu Teng, Cui Hanbin

Abstract excerpt

BACKGROUND AND AIMS: Observational studies have examined serum urate levels in relation to coronary heart disease (CHD) and myocardial infarction (MI). Whether these associations are causal remains controversial, due to confounding factors and reverse causality. We aim to investigate the causality of these associations using Mendelian randomization method. METHODS AND RESULTS: Instrumental variables were obtained...

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PMID: 35197211
DOI: 10.1016/j.numecd.2022.01.022

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