Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Causal Relationship Between Serum Uric Acid and Atherosclerotic Disease: A Mendelian Randomization and Transcriptomic Analysis

28 Jul 2025

Abstract excerpt

Background/Objectives: Elevated serum uric acid levels are associated with the occurrence, development, and adverse events of coronary heart disease (CHD) and CHD risk factors. However, the extent of any pathogenic effect of the serum uric acid on CHD and whether CHD risk factors play a confounding or mediating role are still unclear. Methods: The potential causal associations of serum uric acid with CHD were...

Source

Identifiers

PMID: 40868093
DOI: 10.3390/biomedicines13081838

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Causal Relationship Between Serum Uric Acid and Atherosclerotic Disease: A Mendelian Randomization and Transcriptomic AnalysisPMID 40868093Read ↗

Causal relationship between serum uric acid and cardiovascular disease: a Mendelian randomization studySemantic proximity Read ↗

Uric Acid and Cardiovascular Events: A Mendelian Randomization Study.Semantic proximity Read ↗

Causal relationship between serum uric acid and cardiovascular disease: A Mendelian randomization studySemantic proximity Read ↗

Serum uric acid, body mass index, and cardiovascular diseases: A multiple two-step Mendelian randomization study.Semantic proximity Read ↗

Causal Assessment of Serum Urate Levels in Cardiometabolic Diseases Through a Mendelian Randomization Study.Semantic proximity Read ↗

Serum uric acid levels as a causal factor in hypertension: Insights from Mendelian randomization analysisSemantic proximity Read ↗

Mendelian randomization study of serum uric acid levels and urate-lowering drugs on pulmonary arterial hypertension outcomes.Semantic proximity Read ↗

Uric acid is associated with increased risk of myocardial infarction: results from NHANES 2009-2018 and bidirectional two-sample Mendelian randomization analysis.Semantic proximity Read ↗

Genetic susceptibility to uric acid and selected cardiovascular outcomes: a systematic review and meta-analysis of Mendelian randomization studies.Semantic proximity Read ↗

The causal role of elevated uric acid and waist circumference on the risk of metabolic syndrome components.Semantic proximity Read ↗

Evaluation of the causal effects of blood lipid levels on gout with summary level GWAS data: two-sample Mendelian randomization and mediation analysisSemantic proximity Read ↗

Is Hyperuricemia, an Early-Onset Metabolic Disorder, Causally Associated with Cardiovascular Disease Events in Han Chinese?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.