Article
Isolation of highly enriched primary human microglia for functional studies.
Scientific reports - 18 Jan 2016
Rustenhoven Justin, Park Thomas I-H, Schweder Patrick, Scotter John, Correia Jason, Smith Amy M, Gibbons Hannah M, Oldfield Robyn L, Bergin Peter S, Mee Edward W, Faull Richard L M, Curtis Maurice A, Scott Graham E, Dragunow Mike
Abstract excerpt
Microglia, the resident macrophages of the central nervous system play vital roles in brain homeostasis through clearance of pathogenic material. Microglia are also implicated in neurological disorders through uncontrolled activation and inflammatory responses. To date, the vast majority of microglial studies have been performed using rodent models. Human microglia differ from rodent counterparts in several...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.