Article
Microglia as therapeutic target in central nervous system disorders.
Journal of pharmacological sciences - 1 Nov 2020
Fatoba Oluwaseun, Itokazu Takahide, Yamashita Toshihide
Abstract excerpt
Chronic microglial activation is associated with the pathogenesis of several CNS disorders. Microglia show phenotypic diversity and functional complexity in diseased CNS. Thus, understanding the pathology-specific heterogeneity of microglial behavior is crucial for the future development of microglia-modulating therapy for variety of CNS disorders. This review summarizes up-to-date knowledge on how microglia...
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