Article
Efficient isolation of live microglia with preserved phenotypes from adult mouse brain.
Journal of neuroinflammation - 28 Jun 2012
Nikodemova Maria, Watters Jyoti J
Abstract excerpt
BACKGROUND: Microglial activation plays a key role in the neuroinflammation associated with virtually all CNS disorders, although their role in normal CNS physiology is becoming increasingly appreciated. Neuroinflammation is often assessed by analyzing pro-inflammatory mediators in CNS tissue homogenates, under the assumption that microglia are the main source of these molecules. However, other cell types in the...
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