Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A comparative review of cell culture systems for the study of microglial biology in Alzheimer’s disease

31 May 2012

Abstract excerpt

Over the past two decades, it has become increasingly apparent that Alzheimer's disease neuropathology is characterized by activated microglia (brain resident macrophages) as well as the classic features of amyloid plaques and neurofibrillary tangles. The intricacy of microglial biology has also become apparent, leading to a heightened research interest in this particular cell type. Over the years a number of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Neuroinflammation and Neurodegeneration Mechanisms
Share to Neurological Disease Mechanisms and Treatments

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22651808
DOI: 10.1186/1742-2094-9-115

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A comparative review of cell culture systems for the study of microglial biology in Alzheimer’s diseasePMID 22651808Read ↗

Isolation of highly enriched primary human microglia for functional studies.Semantic proximity Read ↗

Microglia Phenotypes in Aging and Neurodegenerative Diseases.Semantic proximity Read ↗

Subventricular zone microglia possess a unique capacity for massive in vitro expansion.Semantic proximity Read ↗

MicrogliaSemantic proximity Read ↗

A novel cell line from spontaneously immortalized murine microgliaSemantic proximity Read ↗

Different phenotypes of microglia in animal models of Alzheimer diseaseSemantic proximity Read ↗

Exploring the Significance of Microglial Phenotypes and Morphological Diversity in Neuroinflammation and Neurodegenerative Diseases: From Mechanisms to Potential Therapeutic Targets.Semantic proximity Read ↗

Microglia as neuroprotective, immunocompetent cells of the CNSSemantic proximity Read ↗

Homeostatic microglia initially seed and activated microglia later reshape amyloid plaques in Alzheimer's Disease.Semantic proximity Read ↗

Microglia heterogeneity along a spatio–temporal axis: More questions than answersSemantic proximity Read ↗

Roles of microglia in Alzheimer’s disease and impact of new findings on microglial heterogeneity as a target for therapeutic interventionSemantic proximity Read ↗

From theory to therapy: implications from an in vitro model of ramified microglia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.