Article
A Comprehensive Analysis of Primer IDs to Study Heterogeneous HIV-1 Populations.
Journal of molecular biology - 16 Jan 2016
Seifert David, Di Giallonardo Francesca, Töpfer Armin, Singer Jochen, Schmutz Stefan, Günthard Huldrych F, Beerenwinkel Niko, Metzner Karin J
Abstract excerpt
Determining the composition of viral populations is becoming increasingly important in the field of medical virology. While recently developed computational tools for viral haplotype analysis allow for correcting sequencing errors, they do not always allow for the removal of errors occurring in the upstream experimental protocol, such as PCR errors. Primer IDs (pIDs) are one method to address this problem by...
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