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Article

A Bayesian approach to analyse genetic variation within RNA viral populations.

PLoS computational biology - 1 Mar 2011

McKinley Trevelyan J, Murcia Pablo R, Gog Julia R, Varela Mariana, Wood James L N

Abstract excerpt

The development of modern and affordable sequencing technologies has allowed the study of viral populations to an unprecedented depth. This is of particular interest for the study of within-host RNA viral populations, where variation due to error-prone polymerases can lead to immune escape, antiviral resistance and adaptation to new host species. Methods to sequence RNA virus genomes include reverse transcription...

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Identifiers

PMID: 21483482
DOI: 10.1371/journal.pcbi.1002027
PMCID: PMC3068928

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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