Article
Decoding noises in HIV computational genotyping.
Virology - 1 Nov 2017
Jia MingRui, Shaw Timothy, Zhang Xing, Liu Dong, Shen Ye, Ezeamama Amara E, Yang Chunfu, Zhang Ming
Abstract excerpt
Lack of a consistent and reliable genotyping system can critically impede HIV genomic research on pathogenesis, fitness, virulence, drug resistance, and genomic-based healthcare and treatment. At present, mis-genotyping, i.e., background noises in molecular genotyping, and its impact on epidemic surveillance is unknown. For the first time, we present a comprehensive assessment of HIV genotyping quality. HIV...
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