Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ultra-deep sequencing for the analysis of viral populations.

Current opinion in virology - 1 Nov 2011

Beerenwinkel Niko, Zagordi Osvaldo

Abstract excerpt

Next-generation sequencing allows for cost-effective probing of virus populations at an unprecedented level of detail. The massively parallel sequencing approach can detect low-frequency mutations and it provides a snapshot of the entire virus population. However, analyzing ultra-deep sequencing data obtained from diverse virus populations is challenging because of PCR and sequencing errors and short read...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Variation
Share to High-Throughput Nucleotide Sequencing
Share to Sequence Analysis, DNA

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Virus Diseases

Share to Viruses

Source

Identifiers

PMID: 22440844
DOI: 10.1016/j.coviro.2011.07.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ultra-deep sequencing for the analysis of viral populations.PMID 22440844Read ↗

Epidemiological data analysis of viral quasispecies in the next-generation sequencing eraSemantic proximity Read ↗

Deep sequencing: becoming a critical tool in clinical virology.Semantic proximity Read ↗

Within-host nucleotide diversity of virus populations: insights from next-generation sequencing.Semantic proximity Read ↗

Viral genome sequencing methods: benefits and pitfalls of current approachesSemantic proximity Read ↗

Challenges and opportunities in estimating viral genetic diversity from next-generation sequencing dataSemantic proximity Read ↗

V-Phaser 2: variant inference for viral populations.Semantic proximity Read ↗

Deep sequencing analysis of viral infection and evolution allows rapid and detailed characterization of viral mutant spectrum.Semantic proximity Read ↗

Recent advances in inferring viral diversity from high-throughput sequencing data.Semantic proximity Read ↗

Error rates, PCR recombination, and sampling depth in HIV-1 whole genome deep sequencing.Semantic proximity Read ↗

Full-length haplotype reconstruction to infer the structure of heterogeneous virus populations.Semantic proximity Read ↗

Algorithms for Short-Read Viral Haplotype Reconstruction: Challenges, Solutions, and Perspectives.Semantic proximity Read ↗

Accurate <i>in vivo</i> population sequencing uncovers drivers of within-host genetic diversity in virusesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.