Article
Targeted deep sequencing of HIV-1 using the IonTorrentPGM platform.
Journal of virological methods - 1 Sept 2014
Kijak Gustavo H, Sanders-Buell Eric, Harbolick Elizabeth A, Pham Phuc, Chenine Agnes L, Eller Leigh Anne, Rono Kathleen, Robb Merlin L, Michael Nelson L, Kim Jerome H, Tovanabutra Sodsai
Abstract excerpt
The characterization of mixed HIV-1 populations is a key question in clinical and basic research settings. This can be achieved through targeted deep sequencing (TDS), where next-generation sequencing is used to examine in depth a sub-genomic region of interest. This study explores the suitabilit...
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