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Article

Progranulin Protein Levels in Cerebrospinal Fluid in Primary Neurodegenerative Dementias.

Journal of Alzheimer's disease : JAD - 1 Jan 2016

Morenas-Rodríguez Estrella, Cervera-Carles Laura, Vilaplana Eduard, Alcolea Daniel, Carmona-Iragui María, Dols-Icardo Oriol, Ribosa-Nogué Roser, Muñoz-Llahuna Laia, Sala Isabel, Belén Sánchez-Saudinós M, Blesa Rafael, Clarimón Jordi, Fortea Juan, Lleó Alberto

Abstract excerpt

BACKGROUND: Progranulin is implicated in frontotemporal dementia (FTD), but its role in other neurodegenerative disorders is unknown. OBJECTIVE: To investigate the levels of progranulin (PGRN) in cerebrospinal fluid (CSF) in different neurodegenerative dementias and their correlation with levels in plasma in cognitively normal subjects. METHODS: We measured PGRN in CSF in 229 patients with amnestic mild cognitive...

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Identifiers

PMID: 26682689
DOI: 10.3233/JAD-150746

Genes

GRN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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