Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke.

doi:10.1212/WNL.0000000000002263

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Article

Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke.

Neurology - 12 Jan 2016

Traylor Matthew, Zhang Cathy R, Adib-Samii Poneh, Devan William J, Parsons Owen E, Lanfranconi Silvia, Gregory Sarah, Cloonan Lisa, Falcone Guido J, Radmanesh Farid, Fitzpatrick Kaitlin, Kanakis Allison, Barrick Thomas R, Moynihan Barry, Lewis Cathryn M, Boncoraglio Giorgio B, Lemmens Robin, Thijs Vincent, Sudlow Cathie, Wardlaw Joanna, Rothwell Peter M, Meschia James F, Worrall Bradford B, Levi Christopher, Bevan Steve, Furie Karen L, Dichgans Martin, Rosand Jonathan, Markus Hugh S, Rost Natalia

Abstract excerpt

OBJECTIVE: For 3,670 stroke patients from the United Kingdom, United States, Australia, Belgium, and Italy, we performed a genome-wide meta-analysis of white matter hyperintensity volumes (WMHV) on data imputed to the 1000 Genomes reference dataset to provide insights into disease mechanisms. METHODS: We first sought to identify genetic associations with white matter hyperintensities in a stroke population, and...

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Identifiers

PMID: 26674333
DOI: 10.1212/WNL.0000000000002263
PMCID: PMC4731688

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NBEAL1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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