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Article

Multiethnic Genome-Wide Association Study of Cerebral White Matter Hyperintensities on MRI

9 Feb 2015

Abstract excerpt

BACKGROUND: The burden of cerebral white matter hyperintensities (WMH) is associated with an increased risk of stroke, dementia, and death. WMH are highly heritable, but their genetic underpinnings are incompletely characterized. To identify novel genetic variants influencing WMH burden, we conducted a meta-analysis of multiethnic genome-wide association studies. METHODS AND RESULTS: We included 21 079...

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PMID: 25663218
DOI: 10.1161/circgenetics.114.000858

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