17q25 Locus is associated with white matter hyperintensity volume in ischemic stroke, but not with lacunar stroke status.

doi:10.1161/STROKEAHA.113.679936

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

17q25 Locus is associated with white matter hyperintensity volume in ischemic stroke, but not with lacunar stroke status.

Stroke - 1 Jun 2013

Adib-Samii Poneh, Rost Natalia, Traylor Matthew, Devan William, Biffi Alessandro, Lanfranconi Silvia, Fitzpatrick Kaitlin, Bevan Steve, Kanakis Allison, Valant Valerie, Gschwendtner Andreas, Malik Rainer, Richie Alexa, Gamble Dale, Segal Helen, Parati Eugenio A, Ciusani Emilio, Holliday Elizabeth G, Maguire Jane, Wardlaw Joanna, Worrall Bradford, Bis Joshua, Wiggins Kerri L, Longstreth Will, Kittner Steve J, Cheng Yu-Ching, Mosley Thomas, Falcone Guido J, Furie Karen L, Leiva-Salinas Carlos, Lau Benison C, Saleem Khan Muhammed, Sharma Pankaj, Fornage Myriam, Mitchell Braxton D, Psaty Bruce M, Sudlow Cathie, Levi Christopher, Boncoraglio Giorgio B, Rothwell Peter M, Meschia James, Dichgans Martin, Rosand Jonathan, Markus Hugh S

Abstract excerpt

BACKGROUND AND PURPOSE: Recently, a novel locus at 17q25 was associated with white matter hyperintensities (WMH) on MRI in stroke-free individuals. We aimed to replicate the association with WMH volume (WMHV) in patients with ischemic stroke. If the association acts by promoting a small vessel ar...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Brain

Share to Chromosomes, Human, Pair 17

Share to Genome-Wide Association Study

Share to Linear Models

Share to Magnetic Resonance Imaging

Share to Nerve Fibers, Myelinated

Share to Stroke

Source

Open in PubMed Open full text

Identifiers

PMID: 23674528
DOI: 10.1161/STROKEAHA.113.679936
PMCID: PMC3771337

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23674528-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

17q25 Locus is associated with white matter hyperintensity volume in ischemic stroke, but not with lacunar stroke status.PMID 23674528Read ↗

Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke.Semantic proximity Read ↗

Common genetic variation indicates separate etiologies for periventricular and deep white matter hyperintensitiesSemantic proximity Read ↗

Genetic Associations With White Matter Hyperintensities Confer Risk of Lacunar Stroke.Semantic proximity Read ↗

Association of Chr17q25 with cerebral white matter hyperintensities and cognitive impairment: the J-SHIPP study.Semantic proximity Read ↗

Replication study of chr17q25 with cerebral white matter lesion volume.Semantic proximity Read ↗

Cerebral small vessel disease genomics and its implications across the lifespanSemantic proximity Read ↗

Candidate-gene analysis of white matter hyperintensities on neuroimaging.Semantic proximity Read ↗

Do Cerebral Small Vessel Disease and Multiple Sclerosis Share Common Mechanisms of White Matter Injury?Semantic proximity Read ↗

Genetic variation in PLEKHG1 is associated with white matter hyperintensities (n = 11,226)Semantic proximity Read ↗

Replication of Top Loci From COL4A1/2 Associated With White Matter Hyperintensity Burden in Patients With Ischemic Stroke.Semantic proximity Read ↗

Multiethnic Genome-Wide Association Study of Cerebral White Matter Hyperintensities on MRISemantic proximity Read ↗

Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.