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Article

Replication of Top Loci From COL4A1/2 Associated With White Matter Hyperintensity Burden in Patients With Ischemic Stroke.

Stroke - 1 Dec 2020

Li Jiang, Abedi Vida, Zand Ramin, Griessenauer Christoph J

Abstract excerpt

BACKGROUND AND PURPOSE: The purpose of this study was to replicate the top loci associated with white matter hyperintensity (WMH) phenotypes identified by large genome-wide association studies and the loci identified from the previous candidate gene studies. METHODS: A total of 946 Geisinger MyCode patients with acute ischemic stroke with validated European ancestry and magnetic resonance imaging data were...

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Aged
Aged, 80 and over
Cerebral Small Vessel Diseases
Collagen Type IV
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Ischemic Stroke

Magnetic Resonance Imaging

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Identifiers

PMID: 33148145
DOI: 10.1161/STROKEAHA.120.030260
PMCID: PMC8336687

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