Article
Inferring the progression of multifocal liver cancer from spatial and temporal genomic heterogeneity.
Oncotarget - 19 Jan 2016
Shi Jie-Yi, Xing Qingfeng, Duan Meng, Wang Zhi-Chao, Yang Liu-Xiao, Zhao Ying-Jun, Wang Xiao-Ying, Liu Yun, Deng Minghua, Ding Zhen-Bin, Ke Ai-Wu, Zhou Jian, Fan Jia, Cao Ya, Wang Jiping, Xi Ruibin, Gao Qiang
Abstract excerpt
Multifocal tumors developed either as independent tumors or as intrahepatic metastases, are very common in primary liver cancer. However, their molecular pathogenesis remains elusive. Herein, a patient with synchronous two hepatocellular carcinoma (HCC, designated as HCC-A and HCC-B) and one intrahepatic cholangiocarcinoma (ICC), as well as two postoperative recurrent tumors, was enrolled. Multiregional...
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