Article

Molecular evolution in different subtypes of multifocal hepatocellular carcinoma

2023-02-02

Abstract excerpt

<h4>Background: </h4> Multifocal hepatocellular carcinoma (MF-HCC) accounts for >40% of HCCs, demonstrating a poor prognosis than single primary HCCs. Characterizing the dynamic changes of mutation signature along with clonal evolution, quantifying intrahepatic metastatic timing, and investigating the genetic structure in the preneoplastic stage underlying different subtypes of MF-HCC are important for understandi...

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Literature Corpus work: fe7738e8-58fa-589e-b131-946f00ee4e82
DOI: 10.21203/rs.3.rs-2515298/v1

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