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Article

Genomic and transcriptomic profiling reveals key molecules in metastatic potentials and organ-tropisms of hepatocellular carcinoma.

Cellular signalling - 1 Apr 2023

Shi Dong-Min, Dong Shuang-Shuang, Zhou Hong-Xing, Song Dong-Qiang, Wan Jin-Liang, Wu Wei-Zhong

Abstract excerpt

Metastasis is a landmark event for rapid postsurgical relapse and death of HCC patients. Although distinct genomic and transcriptomic profiling of HCC metastasis had been reported previously, the causal relationships of somatic mutants, mRNA levels and metastatic potentials were difficult to be established in clinic. Therefore, 11 human HCC cell lines and 7 monoclonal derivatives with definite metastatic...

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Identifiers

PMID: 36539000
DOI: 10.1016/j.cellsig.2022.110565

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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