Article
Association of common variants in TOMM40/APOE/APOC1 region with human longevity in a Chinese population.
Journal of human genetics - 1 Apr 2016
Lin Rong, Zhang Yunxia, Yan Dongjing, Liao Xiaoping, Gong Gu, Hu Junjie, Fu Yunxin, Cai Wangwei
Abstract excerpt
Apolipoprotein E (APOE), translocase of outer mitochondrial membrane 40 homolog (TOMM40) and apolipoprotein C-I (APOC1) may extend lifespan by marked delay or escape from age-related diseases. This study aimed to elucidate the association of human longevity with genetic variations in TOMM40/APOE/APOC1 region in a Chinese population. Ten tag single-nucleotide polymorphisms (SNPs) in the TOMM40/APOE/APOC1 region...
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