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Article

Genetic variants in PVRL2-TOMM40-APOE region are associated with human longevity in a Han Chinese population.

PloS one - 1 Jan 2014

Lu Fang, Guan Huaijin, Gong Bo, Liu Xiaoqi, Zhu Rongrong, Wang Yong, Qian Jingjing, Zhou Tianqiu, Lan Xiaoyan, Wang Pu, Lin Ying, Ma Shi, Lin He, Zhu Xiong, Chen Rong, Zhu Xianjun, Shi Yi, Yang Zhenglin

Abstract excerpt

PURPOSE: Human longevity results from a number of factors, including genetic background, favorable environmental, social factors and chance. In this study, we aimed to elucidate the association of human longevity with genetic variations in several major candidate genes in a Han Chinese population. METHODS: A case-control association study of 1015 long-lived individuals (aged 90 years or older) and 1725 younger...

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Identifiers

PMID: 24924924
DOI: 10.1371/journal.pone.0099580
PMCID: PMC4055715

Genes

TOMM40
APOE

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Source receipt: pubmed, retrieved 7 Sept 2026.

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