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Article

Potential sites of CFTR activation by tyrosine kinases.

Channels (Austin, Tex.) - 1 Jan 2016

Billet Arnaud, Jia Yanlin, Jensen Timothy J, Hou Yue-Xian, Chang Xiu-Bao, Riordan John R, Hanrahan John W

Abstract excerpt

The CFTR chloride channel is tightly regulated by phosphorylation at multiple serine residues. Recently it has been proposed that its activity is also regulated by tyrosine kinases, however the tyrosine phosphorylation sites remain to be identified. In this study we examined 2 candidate tyrosine residues near the boundary between the first nucleotide binding domain and the R domain, a region which is important...

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Source

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Identifiers

PMID: 26645934
DOI: 10.1080/19336950.2015.1126010
PMCID: PMC4954566

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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