Article
Pathway, in silico and tissue-specific expression quantitative analyses of oesophageal squamous cell carcinoma genome-wide association studies data.
International journal of epidemiology - 1 Feb 2016
Hyland Paula L, Zhang Han, Yang Qi, Yang Howard H, Hu Nan, Lin Shih-Wen, Su Hua, Wang Lemin, Wang Chaoyu, Ding Ti, Fan Jin-Hu, Qiao You-Lin, Sung Hyuna, Wheeler William, Giffen Carol, Burdett Laurie, Wang Zhaoming, Lee Maxwell P, Chanock Stephen J, Dawsey Sanford M, Freedman Neal D, Abnet Christian C, Goldstein Alisa M, Yu Kai, Taylor Philip R
Abstract excerpt
BACKGROUND: Oesophageal cancer is the fourth leading cause of cancer death in China where essentially all cases are histologically oesophageal squamous cell carcinoma (ESCC). Agnostic pathway-based analyses of genome-wide association study (GWAS) data combined with tissue-specific expression quantitative trait loci (eQTL) analysis and publicly available functional data can identify biological pathways and/or...
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