Article
Genome-wide association pathway analysis to identify candidate single nucleotide polymorphisms and molecular pathways for gastric adenocarcinoma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jul 2015
Zhu Hongcheng, Yang Meilin, Zhang Hao, Chen Xiaochen, Yang Xi, Zhang Chi, Qin Qin, Cheng Hongyan, Sun Xinchen
Abstract excerpt
To demonstrate candidate single nucleotide polymorphisms that might affect susceptibility to gastric adenocarcinoma as well as their potential mechanisms and pathway hypotheses, we performed a genome-wide association study dataset of gastric adenocarcinoma. Our study included 472,342 single nucleotide polymorphisms from 2766 cases of gastric cardia adenocarcinoma cases and 11,013 subjects from north central China...
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