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Article

Genetic variants and risk of esophageal squamous cell carcinoma: a GWAS-based pathway analysis.

Gene - 10 Feb 2015

Yang Xi, Zhu Hongcheng, Qin Qin, Yang Yuehua, Yang Yan, Cheng Hongyan, Sun Xinchen

Abstract excerpt

This study was designed to identify candidate single-nucleotide polymorphisms (SNPs) that may affect the susceptibility to esophageal squamous cell carcinoma (ESCC) and elucidate their potential mechanisms to generate SNP-to-gene-to-pathway hypotheses. A genome-wide association study (GWAS) dataset for ESCC, which included 453,852 SNPs from 1898 ESCC patients and 2100 control subjects of Chinese population, was...

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Source

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Identifiers

PMID: 25431829
DOI: 10.1016/j.gene.2014.11.049
PMCID: PMC4696063

Genes

CASP8
MBL2
TDG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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