Article
Systematical identification of key genes and regulatory genetic variants associated with prognosis of esophageal squamous cell carcinoma.
Molecular carcinogenesis - 1 Jun 2024
Gu Linglong, Yue Xinying, Niu Siyuan, Ma Jialing, Liu Shasha, Pan Miaoxin, Song Lina, Su Qianqian, Tan Yuqian, Li Yueping, Chang Jiang
Abstract excerpt
Esophageal squamous cell carcinoma (ESCC) stands as a highly lethal malignancy characterized by pronounced recurrence and metastasis, resulting in a bleak 5-year survival rate. Despite extensive investigations, encompassing genome-wide association studies, the identification of robust prognostic markers has remained elusive. In this study, leveraging four independent data sets comprising 404 ESCC patients, we...
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