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Article

Organic cation transporter 1 variants and gastrointestinal side effects of metformin in patients with Type 2 diabetes.

Diabetic medicine : a journal of the British Diabetic Association - 1 Apr 2016

Dujic T, Causevic A, Bego T, Malenica M, Velija-Asimi Z, Pearson E R, Semiz S

Abstract excerpt

AIMS: Metformin is the most widely used oral anti-diabetes agent and has considerable benefits over other therapies, yet 20-30% of people develop gastrointestinal side effects, and 5% are unable to tolerate metformin due to the severity of these side effects. The mechanism for gastrointestinal side effects and their considerable inter-individual variability is unclear. We have recently shown the association...

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Source

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Identifiers

PMID: 26605869
DOI: 10.1111/dme.13040
PMCID: PMC5064645

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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