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Article

Polymorphism in human organic cation transporters and metformin action.

Pharmacogenomics - 1 Apr 2008

Takane Hiroshi, Shikata Eriko, Otsubo Kenji, Higuchi Shun, Ieiri Ichiro

Abstract excerpt

Considerable interindividual variabilities in clinical efficacy and adverse events are sometimes recognized in the treatment of Type 2 diabetes mellitus with oral antihyperglycemic drugs. Metformin is the most commonly used biguanide in clinical practice, and also improves insulin resistance and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18384255
DOI: 10.2217/14622416.9.4.415

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18384255-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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