Article
Association between parental history and genetic risk scores for coronary heart disease prediction: The population-based CoLaus study.
Atherosclerosis - 1 Jan 2016
Antiochos Panagiotis, Marques-Vidal Pedro, McDaid Aaron, Waeber Gerard, Vollenweider Peter
Abstract excerpt
BACKGROUND AND AIMS: Parental history (PH) and genetic risk scores (GRSs) are separately associated with coronary heart disease (CHD), but evidence regarding their combined effects is lacking. We aimed to evaluate the joint associations and predictive ability of PH and GRSs for incident CHD. METHODS: Data for 4283 Caucasians were obtained from the population-based CoLaus Study, over median follow-up time of 5.6...
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