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Article

Autophosphorylation of alpha isoform of calcium/calmodulin-dependent kinase II regulates alcohol addiction-related behaviors.

Addiction biology - 1 Mar 2017

Mijakowska Zofia, Łukasiewicz Kacper, Ziółkowska Magda, Lipiński Michał, Trąbczyńska Anna, Matuszek Żaneta, Łęski Szymon, Radwanska Kasia

Abstract excerpt

The development of addiction is associated with a dysregulation of glutamatergic transmission in the brain reward circuit. α isoform of calcium/calmodulin-dependent kinase II (αCaMKII) is one of the key proteins that regulates structural and functional plasticity of glutamatergic synapses. αCaMKII activity can be controlled by the autophosphorylation of threonine 286. The role of this autophosphorylation in the...

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Identifiers

PMID: 26572936
DOI: 10.1111/adb.12327

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Autophosphorylation of alpha isoform of calcium/calmodulin-dependent kinase II regulates alcohol addiction-related behaviors.PMID 26572936Read ↗

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