Article
Genetic Variation in the Catechol-O-Methyl Transferase Val108/158Met Is Linked to the Caudate and Posterior Cingulate Cortex Volume in Healthy Subjects: Voxel-Based Morphometry Analysis of Brain Magnetic Resonance Imaging.
PloS one - 1 Jan 2015
Watanabe Keita, Kakeda Shingo, Yoshimura Reiji, Ide Satoru, Hayashi Kenji, Katsuki Asuka, Umene-Nakano Wakako, Watanabe Rieko, Abe Osamu, Korogi Yukunori
Abstract excerpt
The effect of the catechol-O-methyltransferase (COMT) Val158Met polymorphism on brain morphology has been investigated but remains controversial. We hypothesized that a comparison between Val/Val and Val/Met individuals, which may represent the most different combinations concerning the effects of the COMT genotype, may reveal new findings. We investigated the brain morphology using 3-Tesla magnetic resonance...
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