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Article

The COMT Val158Met polymorphism and temporal lobe morphometry in healthy adults.

Psychiatry research - 15 Jul 2007

Taylor Warren D, Züchner Stephan, Payne Martha E, Messer Denise F, Doty Tracy J, MacFall James R, Beyer John L, Krishnan K Ranga R

Abstract excerpt

We examined the relationship between COMT Val158Met genotype and temporal lobe volumes, including the caudate as a control region. Thirty-one healthy subjects completed 1.5T brain MRI and genotyping. After controlling for demographics, Val158 allele homozygotes exhibited significantly smaller temporal lobe and hippocampal volumes, with a trend for smaller amygdala volumes.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17521892
DOI: 10.1016/j.pscychresns.2007.01.005
PMCID: PMC1950247

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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