Article
The importance of identifying functional Val158Met polymorphism in catechol-O- Methyltransferase when assessing MRI-based volumetric measurements in major depressive disorder.
Brain imaging and behavior - 1 Dec 2020
Serrano-Sosa Mario, Sampathgiri Kruthika, Spuhler Karl Douglas, DeLorenzo Christine, Parsey Ramin, Huang Chuan
Abstract excerpt
Many studies have shown volumetric differences in the hippocampus between COMT gene polymorphisms and other studies have shown differences between depressed patients and controls; yet, few studies have been completed to identify the volumetric differences when taking both factors into consideration. Using voxel-based morphology (VBM) we investigated, in major depressive disorder (MDD) patients and healthy...
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