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Article

IL28B gene polymorphisms and Th1/Th2 cytokine levels might be associated with HTLV-associated arthropathy.

Cytokine - 1 Jan 2016

de Sá Keyla Santos Guedes, Santana Bárbara Brasil, de Souza Ferreira Tuane Carolina, Sousa Rita Catarina Medeiros, Caldas Cezar Augusto Muniz, Azevedo Vânia Nakauth, Feitosa Rosimar Neris Martins, Machado Luiz Fernando Almeida, de Oliveira Guimarães Ishak Marluísa, Ishak Ricardo, Vallinoto Antonio Carlos Rosário

Abstract excerpt

The present study is the first investigation of the association between single nucleotide polymorphisms (SNPs - rs8099917, rs12979860 and rs8103142) of the IL28B gene and the development of human T-lymphotropic virus (HTLV)-associated arthropathy (HAA). Individuals with HAA exhibited low interleukin (IL) 6 (p<0.05) and high IL-10 (p<0.05) levels compared with asymptomatic patients. TNF-α/CD4(+) T cell count,...

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PMID: 26546777
DOI: 10.1016/j.cyto.2015.11.004

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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IL28B gene polymorphisms and Th1/Th2 cytokine levels might be associated with HTLV-associated arthropathy.PMID 26546777Read ↗

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