Article
Association between HLA alleles and HAM/TSP in individuals infected with HTLV-1.
Journal of neurology - 1 Oct 2013
Treviño Ana, Vicario Jose L, Lopez Mariola, Parra Patricia, Benito Rafael, Ortiz de Lejarazu Raul, Ramos Jose M, Del Romero Jorge, de Mendoza Carmen, Soriano Vincent
Abstract excerpt
HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) develops in less than 5 % of HTLV-1 carriers. It is unclear which factors trigger the development of disease. The aim of this study was to explore the influence of HLA alleles on the development of HAM/TSP. A total of 40 HTLV-1-infected individuals belonging to the Spanish HTLV-1 cohort were examined. HTLV-1 proviral load was measured by...
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