Article
A significant association between CXCL10 -1447 A > G and IL18 -607 C > A gene polymorphism with human T-cell lymphotropic virus type 1 associated myelopathy/tropical spastic paraparesis (HAM-TSP), a case-control report from city of Mashhad, Iran.
Journal of neurovirology - 1 Apr 2021
Rafatpanah Houshang, Poursina Zohreh, Boostani Reza, Marzouni Hadi Zare, Atabaki Mahdi, Hosseini Reza Farid, Tavakkol-Afshari Jalil, Mohammadi Mojgan
Abstract excerpt
Human T-cell lymphotropic virus type 1 (HTLV-1) is the first isolated retrovirus from humans, and 2-3% of infected individuals suffer from HTLV-1 associated myelopathy tropical spastic paraparesis (HAM-TSP). Previous studies indicated that the risk of HAM-TSP could be correlated with the individuals' genetic alterations. Mashhad is one of the areas infected with HTLV-1 in Iran. This study designed to examine the...
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