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Interleukin-18 and interferon-gamma polymorphisms are implicated on proviral load and susceptibility to human T-lymphotropic virus type 1 infection.

Tissue antigens - 1 Aug 2012

Rocha-Júnior M C, Haddad R, Cilião Alves D C, de Deus Wagatsuma V M, Mendes-Junior C T, Deghaide N H S, Takayanagui O M, Covas D T, Donadi E A, Kashima S

Abstract excerpt

Interleukin-18 (IL-18) and interferon-gamma (IFN-γ) exert important functions in both innate and adaptive immune responses against intracellular pathogens and viruses. Previous studies suggested that host genetic factors, including cytokines gene polymorphisms, could be involved in the pathogenesis of human T-cell leukemia virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Thus,...

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Identifiers

PMID: 22587568
DOI: 10.1111/j.1399-0039.2012.01887.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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