Article
HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis Is Not Associated with SNP rs12979860 of the IL-28B Gene.
Mediators of inflammation - 1 Jan 2015
Vallinoto Antonio C R, Santana Bárbara Brasil, Sá Keyla S G, Ferreira Tuane C S, Sousa Rita Catarina M, Azevedo Vânia N, Feitosa Rosimar N M, Machado Luiz Fernando A, Ishak Marluísa O G, Ishak Ricardo
Abstract excerpt
The present study investigated the association between the rs12979860 polymorphism in the IL-28B gene and HTLV-1 infection as well as the development of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). HTLV-1-infected patients (26 HAM/TSP symptomatic and 53 asymptomatic) and 300 seronegative healthy controls were investigated. Plasma levels of the cytokines TNF-α, TNF-β, IL-8, IL-10, IL-6, and...
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