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The influence of human leukocyte antigen class I loci -A, -B, -C, and class II HLA-DRB1 alleles in a Brazilian HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) population and association with disease outcome and proviral load

2022-12-29

Abstract excerpt

<title>Abstract</title> <p>Around ten million people are infected with HTLV-1 worldwide, and 1–4% develop HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), characterized by an important degeneration of the spinal cord, that can lead to death. Distinct HLA alleles have been associated with either HAM/TSP susceptibility or protection. However, these HLA alleles set may change according to the pop...

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Literature Corpus work
35c3a510-30b5-5df5-a18e-f0eeffac2f04
DOI
10.21203/rs.3.rs-1697475/v2
Open publication

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The influence of human leukocyte antigen class I loci -A, -B, -C, and class II HLA-DRB1 alleles in a Brazilian HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) population and association with disease outcome and proviral loadDOI 10.21203/rs.3.rs-1697475/v2
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