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Article

CSF Nrf2 and HSPA8 in Parkinson's disease patients with and without LRRK2 gene mutations.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Mar 2016

Loeffler David A, Smith Lynnae M, Coffey Mary P, Aasly Jan O, LeWitt Peter A

Abstract excerpt

Leucine-rich repeat kinase 2 (LRRK2) gene mutations are the most common genetic cause of Parkinson's disease (PD). CSF specimens from LRRK2 + PD patients and healthy LRRK2 mutation carriers are, therefore, useful for biomarker studies. This study examined the hypothesis that differences are present between subjects with sporadic PD (sPD), PD carriers of LRRK2 mutations (LRRK2 + PD), healthy control subjects...

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Source

Identifiers

PMID: 26526034
DOI: 10.1007/s00702-015-1479-0

Genes

HSPA8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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