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Article

Ser(P)‐1292 LRRK2 in urinary exosomes is elevated in idiopathic Parkinson's disease

14 Jun 2016

Abstract excerpt

BACKGROUND: Mutations in Leucine-rich repeat kinase 2 (LRRK2) enhance levels of the autophosphorylated LRRK2 protein and are the most common known cause of inherited Parkinson's disease (PD). LRRK2 has been further implicated in susceptibility to idiopathic PD in genetic association studies. OBJECTIVE: The objective of this study was to compare autophosphorylated Ser(P)-1292 LRRK2 levels from biobanked urine...

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PMID: 27297049
DOI: 10.1002/mds.26686

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