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Article

Role of the Transcription Factor Nrf2 in Parkinson’s Disease: New Insights

2017-01-01

Abstract excerpt

Parkinson’s disease (PD) is a slow progressive neurodegenerative disorder associated with motor and nonmotor symptoms, with no neuroprotective therapies. This chronic disease is characterized by loss of dopaminergic neurons from the sustantia nigra pars compacta and the presence of cytoplasmic α-synuclein-positive inclusions called Lewy bodies in the surviving neurons. Although PD has unknown etiology, familiar fo...

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Literature Corpus work
1d50ced0-4f3e-5a24-bc3f-df6fe800d16d
DOI
10.4172/2161-0460.1000340
Open publication

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Role of the Transcription Factor Nrf2 in Parkinson’s Disease: New InsightsDOI 10.4172/2161-0460.1000340
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