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Article

eQTL networks unveil enriched mRNA master integrators downstream of complex disease-associated SNPs.

Journal of biomedical informatics - 1 Dec 2015

Li Haiquan, Pouladi Nima, Achour Ikbel, Gardeux Vincent, Li Jianrong, Li Qike, Zhang Hao Helen, Martinez Fernando D, 'Skip' Garcia Joe G N, Lussier Yves A

Abstract excerpt

The causal and interplay mechanisms of Single Nucleotide Polymorphisms (SNPs) associated with complex diseases (complex disease SNPs) investigated in genome-wide association studies (GWAS) at the transcriptional level (mRNA) are poorly understood despite recent advancements such as discoveries reported in the Encyclopedia of DNA Elements (ENCODE) and Genotype-Tissue Expression (GTex). Protein interaction network...

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Identifiers

PMID: 26524128
DOI: 10.1016/j.jbi.2015.10.010
PMCID: PMC4684766

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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